Medical University of South Carolina (MUSC) Online Nursing Programs

The Medical University of South Carolina (MUSC) College of Nursing offers a wide range of online nurse practitioner programs designed to prepare graduates for advanced practice roles in today’s dynamic healthcare environment. As South Carolina’s only integrated academic health sciences center, this university delivers nationally recognized MSN, BSN-to-DNP (MSN/DNP dual degree), and post-master’s certificate options for both aspiring and experienced nurses seeking a flexible, high-caliber education.

The MSN program is designed for post-baccalaureate prepared nurses, while the BSN-to-DNP (MSN/DNP dual degree) is also an option for post-baccalaureate prepared nurses who want preparation at the highest clinical level. The PMHNP certificate is designed for current APRNs with an MSN or DNP who want to obtain a second certification in psychiatric mental health nursing. Across these pathways, MUSC describes a learning environment focused on advanced clinical nursing practice, leadership, policy, scholarship, and evidence-based care.

The college’s online master of science in nursing (MSN) program provides five population-focused NP specializations. These include:

  • Acute Care Pediatric Nurse Practitioner (ACPNP)
  • Adult-Gerontology Nurse Practitioner (AGNP)
  • Family nurse practitioner (FNP)
  • Pediatric nurse practitioner (PNP)
  • Psychiatric-mental health nurse practitioner (PMHNP)

Didactic coursework for these online MSN programs is delivered primarily online, with a few mandatory campus-based intensives. Each MSN specialty is designed to cultivate excellence in leadership and clinical care, grounded in interprofessional collaboration, evidence-based practice, and integrated behavioral health training. Graduates are prepared to sit for national board certification in their area of specialization.

Designed for nurses interested in the highest level of clinical practice, the BSN-to-doctor of nursing practice (BSN-to-DNP) dual-degree program also offers the same five advanced nurse practitioner specializations. This pathway confers both an MSN and a DNP degree upon graduation, integrating advanced coursework in health policy, leadership, translational research, and systems design with robust clinical preparation at affiliated sites. Students participate in several multi-day campus immersions, developing critical skills. The program welcomes new BSN graduates as well as experienced RNs, with no GRE requirement and flexible start times.

For experienced APRNs seeking to further expand their scope, MUSC also offers a post-master’s certificate in psychiatric-mental health nurse practitioner (PMHNP). This flexible certificate program is designed for those already nationally certified in another APRN population focus and provides comprehensive education in medication management, psychotherapy, and psychiatric assessment across the lifespan. Students benefit from expert faculty members, real-world clinical placements arranged in their home state or local region, and rich interprofessional learning opportunities.

Each area of study has a distinct focus. The ACPNP specialization prepares nurses to care for children and young adults with complex, critical, and life-threatening conditions in settings such as pediatric intensive care units, emergency departments, and specialized hospital units. The AGNP specialization focuses on primary care for adults across the lifespan from early adulthood through advanced age, with attention to chronic disease treatment, disease prevention, wellness promotion, and geriatric care.

The FNP specialization prepares nurses to provide person-centered primary care to patients of all ages, from pediatrics to geriatrics, with an emphasis on continuity of care and holistic treatment planning. The PNP specialization focuses on primary care for children from infancy through young adulthood, including preventive care, developmental milestones, disease management, and family-centered education. The PMHNP specialization prepares nurses to provide psychiatric care across the lifespan through psychotherapy, medication management, therapeutic intervention, and care coordination for mental health and substance use disorders.

The ACPNP option includes an additional experience requirement. For both the MSN and DNP/MSN versions of this specialization, applicants must have at least one year of experience gained within the past five years in a pediatric intensive care unit or a comparable high-acuity pediatric clinical setting.

All nursing programs are accredited by the Commission on Collegiate Nursing Education (CCNE), and MUSC is regionally accredited by the Southern Association of Colleges and Schools Commission on Colleges (SACSCOC).

Upon graduation, students are eligible to pursue board certification and licensure in their chosen advanced practice nursing specialty. The Medical University of South Carolina is located in Charleston, SC.

What to Expect from Medical University of South Carolina (MUSC) Online Nursing Programs

Admission Requirements: The MSN and BSN-to-DNP (MSN/DNP dual degree) programs at MUSC share a common admissions structure for post-baccalaureate prepared nurses. Applicants must have a BSN from a nationally accredited program, maintain a preferred cumulative GPA of 3.0 or higher in nursing courses, hold an unencumbered and active RN license in the state where practicums will be conducted, and have completed undergraduate coursework in statistics.

Applicants to these programs must also submit the NursingCAS application, the MUSC application, official transcripts from all institutions attended, three letters of recommendation, a personal essay, an updated resume, and any program-specific supplemental materials sent after application submission. Official immunization records are required upon admission, and TOEFL scores are required for applicants whose native language is not English.

The ACPNP specialization has an additional requirement in both the MSN and DNP/MSN pathways. Applicants must have at least one year of experience gained within the past five years in a pediatric intensive care unit or a comparable high-acuity pediatric clinical setting.

Applicants to the post-graduate PMHNP certificate must hold a BSN as well as an MSN or DNP from nationally accredited programs, maintain an unencumbered and active APRN license in the state where practicums will be conducted, maintain a preferred cumulative GPA of 3.0 or higher in nursing courses, and provide evidence of national certification as a nurse practitioner in acute or primary care or as a clinical nurse specialist in psychiatric mental health nursing. Applicants must also have completed pathophysiology, pharmacology, and physical assessment courses for the lifespan.

For the PMHNP certificate, acute care or primary care nurse practitioners and clinical nurse specialists in psychiatric mental health nursing may apply, while CRNAs and non-psychiatric mental health CNSs are not eligible. The application also requires NursingCAS and MUSC applications, three letters of recommendation, official transcripts, a personal essay, an updated resume, supplemental materials, immunization records, and TOEFL scores when applicable. GRE scores are not required for this program.

State Restrictions: The Medical University of South Carolina accepts students from most states and is an NC-SARA participant. However, the program does not accept students from Arizona, Louisiana, Mississippi, Oregon, or Washington at this time. Interested students from eligible states should contact the MUSC School of Nursing to verify eligibility. Additionally, prospective students should contact the licensing board of their specific state of residence to determine if the program meets state requirements for NP licensure. Finally, MUSC cannot admit international students requiring an F-1 visa. Applicants must be U.S. citizens, permanent residents, or have a non-immigrant visa that allows study in the U.S.

Study Plan: The Medical University of South Carolina (MUSC) College of Nursing offers a flexible study plan designed to accommodate both part-time and full-time students pursuing advanced nursing roles. The 76-credit BSN-to-DNP dual-degree program can be completed in as little as three years full-time or four years part-time, while the 60-credit MSN program typically requires two to three years, depending on course sequence and student pace.

Coursework is delivered primarily online, while select courses require brief, on-campus learning intensives. Throughout their programs, students participate in multiple campus immersions, engaging in hands-on clinical experiences. Clinical practical training is arranged locally so students can complete required preceptorships in their own communities under the guidance of expert faculty members and approved preceptors.

For the post-master’s certificate in PMHNP, the program is designed for working APRNs and may be completed on a flexible, part-time schedule to accommodate professional responsibilities. This certificate consists of 23 credits and is designed to be completed in four semesters.

BSN-to-DNP Curriculum: The BSN-to-DNP dual-degree program at MUSC comprises 76 credits. The academic plan covers foundational advanced practice competencies through courses such as advanced pathophysiology; applied epidemiology and biostatistics; advanced clinical assessment and reasoning; advanced pharmacotherapeutics; informatics in health care delivery; evidence-based practice, quality, and safety; advanced health policy and advocacy; practice inquiry and IRB; organizational theory and health care systems; applied health care economics and finance; and frameworks for leadership.

Core clinical coursework consists of advanced care management I-III, role practicum, and two sequential residency courses. The clinical courses are specific to the specialization.

MSN Curriculum: The 100 percent online master of science in nursing (MSN) program prepares graduates for advanced practice roles in five specializations: FNP, AGNP, ACPNP, PNP, and PMHNP. Students complete a curriculum that mirrors DNP foundational coursework but with a focused graduate plan of study, typically comprising 59 to 60 credits.

Required courses include advanced pathophysiology; advanced clinical assessment and reasoning; advanced pharmacotherapeutics; informatics in healthcare delivery; and core leadership and policy courses. Specialty-specific courses and supervised clinical training allow students to master clinical care within their population focus. Select in-person intensives and simulation experiences are also required.

Post-Master’s Certificate in PMHNP: For APRNs and clinical nurse specialists seeking board certification as a psychiatric-mental health nurse practitioner, MUSC’s post-master’s certificate program comprises 23 credits. Core subjects include neuroscience for advanced APRNs; neuroscience of psychotherapeutic interventions and psychopharmacology; and a three-semester sequence of advanced care management in psychiatric-mental health. Students complete supervised clinical hours at approved sites, gaining experience in assessment, therapy, psychopharmacology, and evidence-based psychiatric care across the lifespan.

Online Experience: The Medical University of South Carolina uses Blackboard Open as its online Learning Management System (LMS). The MSN program is offered online, the DNP/MSN dual degree uses a hybrid format with mostly online coursework, and the PMHNP certificate is delivered online with flexible coursework for advanced practice nurses. MUSC uses the Panopto video content management system to capture lectures. The College of Nursing faculty and academic advisors offer office hours and meetings through videoconferencing, email, and phone. The Technology Help Desk offers technical support Monday through Friday. Other student services include admissions counseling, online library and bookstore services, and career counseling.

On-Site Requirements: Although these programs use online delivery, some in-person components are still required. The MSN program includes a few courses that require a visit to campus, and the DNP/MSN dual degree includes focused on-campus intensives. The PMHNP certificate also includes in-person clinical experiences at approved sites, and all three pathways include clinical learning in direct patient care settings.

Paying for Medical University of South Carolina (MUSC) Online Nursing Programs

Each MUSC online program’s tuition is listed in its table below. In addition to tuition, there may also be an online program fee and travel expenses for campus visits. Interested nursing students should contact the MUSC College of Nursing for more details.

The Medical University of South Carolina may offer grants, scholarships, and loans to online graduate students, including unsubsidized federal graduate loans, according to the FAFSA. Graduate nursing students are also encouraged to inquire with their employers as to the possibility of a tuition reimbursement program or tuition discount. Additionally, MUSC DNP students may seek outside opportunities such as organizational or community scholarships.

Medical University of South Carolina (MUSC)

MUSC offers FNP, AGPCNP, PNP, and PMHNP degree options for their BSN to DNP program that includes up to 7 campus immersions and is based on a scientific foundation of evidence-based practice in order to influence quality of care, clinical decision-making, and leadership in nursing.

APRN Programs

BSN to DNP – Acute Care Pediatric NP (MSN/DNP Dual Degree)
BSN to DNP – Adult-Gerontology Health NP (MSN/DNP Dual Degree)
BSN to DNP – Family NP (MSN/DNP Dual Degree)
BSN to DNP – Pediatric NP (MSN/DNP Dual Degree)
BSN to DNP – Psychiatric-Mental Health NP (MSN/DNP Dual Degree)
MSN – Acute Care Pediatric Nurse Practitioner
MSN – Adult-Gerontology Nurse Practitioner
MSN – Family Nurse Practitioner
MSN – Pediatric Nurse Practitioner
MSN – Psychiatric-Mental Health Nurse Practitioner
Post-Graduate Certificate – Psychiatric-Mental Health NP

Campus Address

171 Ashley Avenue
Charleston, South Carolina 29425

Medical University of South Carolina (MUSC) – BSN to DNP – Acute Care Pediatric NP (MSN/DNP Dual Degree)

Program Essentials

Degree Level

DNP – Doctor of Nursing Practice

Specialization

PNP – Pediatric Nurse Practitioner

Program Start Dates

Fall

100% Online?

No

Campus Visits Required

3-5

Credits Needed to Graduate

76

Clinical Hours Needed to Graduate

1165

Program Accreditation

CCNE – Commission on Collegiate Nursing Education

Program Admissions

Level of Education Required?

BSN – Bachelor of Science in Nursing

GRE or GMAT Required?

No GRE Required

GPA Required?

3.0 or higher

State Restrictions? (Will Not Accept From…)

AZ, LA, OR, MS, WA

Program Tuition

Credit Hours

76

Average Cost Per Credit (state resident)

$905.00

Estimated Total Tuition (state resident)

$68,780.00

Average Cost Per Credit (non-resident)

$1,190.00

Estimated Total Tuition (non-resident)

$90,440.00

Medical University of South Carolina (MUSC) – BSN to DNP – Adult-Gerontology Health NP (MSN/DNP Dual Degree)

Program Essentials

Degree Level

DNP – Doctor of Nursing Practice

Specialization

AGNP – Adult-Gerontology Nurse Practitioner

Program Start Dates

Fall

100% Online?

No

Campus Visits Required

3-5

Credits Needed to Graduate

76

Clinical Hours Needed to Graduate

1,165

Program Accreditation

CCNE – Commission on Collegiate Nursing Education

Program Admissions

Level of Education Required?

BSN – Bachelor of Science in Nursing

GRE or GMAT Required?

No GRE Required

GPA Required?

3.0 or higher

State Restrictions? (Will Not Accept From…)

None

Program Tuition

Credit Hours

76

Average Cost Per Credit (state resident)

$905.00

Estimated Total Tuition (state resident)

$68,780.00

Average Cost Per Credit (non-resident)

$1,190.00

Estimated Total Tuition (non-resident)

$90,440.00

Medical University of South Carolina (MUSC) – BSN to DNP – Family NP (MSN/DNP Dual Degree)

Program Essentials

Degree Level

DNP – Doctor of Nursing Practice

Specialization

FNP – Family Nurse Practitioner

Program Start Dates

Fall

100% Online?

No

Campus Visits Required

3-5

Credits Needed to Graduate

76

Clinical Hours Needed to Graduate

1,165

Program Accreditation

CCNE – Commission on Collegiate Nursing Education

Program Admissions

Level of Education Required?

BSN – Bachelor of Science in Nursing

GRE or GMAT Required?

No GRE Required

GPA Required?

3.0 or higher

State Restrictions? (Will Not Accept From…)

None

Program Tuition

Credit Hours

76

Average Cost Per Credit (state resident)

$905.00

Estimated Total Tuition (state resident)

$68,780.00

Average Cost Per Credit (non-resident)

$1,190.00

Estimated Total Tuition (non-resident)

$90,440.00

Medical University of South Carolina (MUSC) – BSN to DNP – Pediatric NP (MSN/DNP Dual Degree)

Program Essentials

Degree Level

DNP – Doctor of Nursing Practice

Specialization

PNP – Pediatric Nurse Practitioner

Program Start Dates

Fall

100% Online?

No

Campus Visits Required

3-5

Credits Needed to Graduate

76

Clinical Hours Needed to Graduate

1,165

Program Accreditation

CCNE – Commission on Collegiate Nursing Education

Program Admissions

Level of Education Required?

BSN – Bachelor of Science in Nursing

GRE or GMAT Required?

No GRE Required

GPA Required?

3.0 or higher

State Restrictions? (Will Not Accept From…)

None

Program Tuition

Credit Hours

76

Average Cost Per Credit (state resident)

$905.00

Estimated Total Tuition (state resident)

$68,780.00

Average Cost Per Credit (non-resident)

$1,190.00

Estimated Total Tuition (non-resident)

$90,440.00

Medical University of South Carolina (MUSC) – BSN to DNP – Psychiatric-Mental Health NP (MSN/DNP Dual Degree)

Program Essentials

Degree Level

DNP – Doctor of Nursing Practice

Specialization

PMHNP – Psychiatric-Mental Health Nurse Practitioner

Program Start Dates

Fall

100% Online?

No

Campus Visits Required

3-5

Credits Needed to Graduate

76

Clinical Hours Needed to Graduate

1,165

Program Accreditation

CCNE – Commission on Collegiate Nursing Education

Program Admissions

Level of Education Required?

BSN – Bachelor of Science in Nursing

GRE or GMAT Required?

No GRE Required

GPA Required?

3.0 or higher

State Restrictions? (Will Not Accept From…)

None

Program Tuition

Credit Hours

76

Average Cost Per Credit (state resident)

$905.00

Estimated Total Tuition (state resident)

$68,780.00

Average Cost Per Credit (non-resident)

$1,190.00

Estimated Total Tuition (non-resident)

$90,440.00

Medical University of South Carolina (MUSC) – MSN – Acute Care Pediatric Nurse Practitioner

Program Essentials

Degree Level

MSN – Master of Science in Nursing

Specialization

PNP – Pediatric Nurse Practitioner

Program Start Dates

Fall

100% Online?

No

Campus Visits Required

3

Credits Needed to Graduate

60

Clinical Hours Needed to Graduate

765

Program Accreditation

CCNE – Commission on Collegiate Nursing Education

Program Admissions

Level of Education Required?

BSN – Bachelor of Science in Nursing

GRE or GMAT Required?

No GRE Required

GPA Required?

3.0 or higher

State Restrictions? (Will Not Accept From…)

AZ, LA, OR, WA

Program Tuition

Credit Hours

60

Average Cost Per Credit (state resident)

$905.00

Estimated Total Tuition (state resident)

$54,300.00

Average Cost Per Credit (non-resident)

$1,190.00

Estimated Total Tuition (non-resident)

$71,400.00

Medical University of South Carolina (MUSC) – MSN – Adult-Gerontology Nurse Practitioner

Program Essentials

Degree Level

MSN – Master of Science in Nursing

Specialization

AGNP – Adult-Gerontology Nurse Practitioner

Program Start Dates

Fall

100% Online?

No

Campus Visits Required

3

Credits Needed to Graduate

60

Clinical Hours Needed to Graduate

765

Program Accreditation

CCNE – Commission on Collegiate Nursing Education

Program Admissions

Level of Education Required?

BSN – Bachelor of Science in Nursing

GRE or GMAT Required?

No GRE Required

GPA Required?

3.0 or higher

State Restrictions? (Will Not Accept From…)

AZ, LA, OR, WA

Program Tuition

Credit Hours

60

Average Cost Per Credit (state resident)

$905.00

Estimated Total Tuition (state resident)

$54,300.00

Average Cost Per Credit (non-resident)

$1,190.00

Estimated Total Tuition (non-resident)

$71,400.00

Medical University of South Carolina (MUSC) – MSN – Family Nurse Practitioner

Program Essentials

Degree Level

MSN – Master of Science in Nursing

Specialization

FNP – Family Nurse Practitioner

Program Start Dates

Fall

100% Online?

No

Campus Visits Required

3

Credits Needed to Graduate

60

Clinical Hours Needed to Graduate

765

Program Accreditation

CCNE – Commission on Collegiate Nursing Education

Program Admissions

Level of Education Required?

BSN – Bachelor of Science in Nursing

GRE or GMAT Required?

No GRE Required

GPA Required?

3.0 or higher

State Restrictions? (Will Not Accept From…)

AZ, LA, OR, WA

Program Tuition

Credit Hours

60

Average Cost Per Credit (state resident)

$905.00

Estimated Total Tuition (state resident)

$54,300.00

Average Cost Per Credit (non-resident)

$1,190.00

Estimated Total Tuition (non-resident)

$71,400.00

Medical University of South Carolina (MUSC) – MSN – Pediatric Nurse Practitioner

Program Essentials

Degree Level

MSN – Master of Science in Nursing

Specialization

PNP – Pediatric Nurse Practitioner

Program Start Dates

Fall

100% Online?

No

Campus Visits Required

3

Credits Needed to Graduate

60

Clinical Hours Needed to Graduate

765

Program Accreditation

CCNE – Commission on Collegiate Nursing Education

Program Admissions

Level of Education Required?

BSN – Bachelor of Science in Nursing

GRE or GMAT Required?

No GRE Required

GPA Required?

3.0 or higher

State Restrictions? (Will Not Accept From…)

AZ, LA, OR, WA

Program Tuition

Credit Hours

60

Average Cost Per Credit (state resident)

$905.00

Estimated Total Tuition (state resident)

$54,300.00

Average Cost Per Credit (non-resident)

$1,190.00

Estimated Total Tuition (non-resident)

$71,400.00

Medical University of South Carolina (MUSC) – MSN – Psychiatric-Mental Health Nurse Practitioner

Program Essentials

Degree Level

MSN – Master of Science in Nursing

Specialization

PMHNP – Psychiatric-Mental Health Nurse Practitioner

Program Start Dates

Fall

100% Online?

No

Campus Visits Required

3

Credits Needed to Graduate

60

Clinical Hours Needed to Graduate

765

Program Accreditation

CCNE – Commission on Collegiate Nursing Education

Program Admissions

Level of Education Required?

BSN – Bachelor of Science in Nursing

GRE or GMAT Required?

No GRE Required

GPA Required?

3.0 or higher

State Restrictions? (Will Not Accept From…)

AZ, LA, OR, WA

Program Tuition

Credit Hours

60

Average Cost Per Credit (state resident)

$905.00

Estimated Total Tuition (state resident)

$54,300.00

Average Cost Per Credit (non-resident)

$1,190.00

Estimated Total Tuition (non-resident)

$71,400.00

Medical University of South Carolina (MUSC) – Post-Graduate Certificate – Psychiatric-Mental Health NP

Program Essentials

Degree Level

Post-Master Certificate – Post-Graduate (Post-MSN) Nursing Certificate

Specialization

PMHNP – Psychiatric-Mental Health Nurse Practitioner

Program Start Dates

Spring, Summer, Fall

100% Online?

No

Campus Visits Required

2

Credits Needed to Graduate

23

Clinical Hours Needed to Graduate

765

Program Accreditation

CCNE – Commission on Collegiate Nursing Education

Program Admissions

Level of Education Required?

MSN – Master of Science in Nursing

GRE or GMAT Required?

No GRE Required

GPA Required?

3.0 or higher

State Restrictions? (Will Not Accept From…)

AZ, LA, OR, WA

Program Tuition

Credit Hours

23

Average Cost Per Credit (state resident)

$905.00

Estimated Total Tuition (state resident)

$20,815.00

Average Cost Per Credit (non-resident)

$1,190.00

Estimated Total Tuition (non-resident)

$27,370.00

Tuition is calculated based on credits, at the published tuition rate. Rates may change, so please check here for the latest tuition information. For programs with variable tuition rates, we use the rates for part-time students. “Resident” and “non-resident” refer to the student’s school-recognized state residency status. Tuition number represents the cost of tuition for the entire program, not per semester or year. Estimated total tuition does not include additional fees.

Sara Navratil

Sara Navratil

Writer

Sara Navratil is a freelance writer and a Certified Canfield Success Principles Trainer. She’s the owner of Sara Liza Life, a company dedicated to helping people rewrite their lives. She enjoys researching and writing about healthcare-related topics, including information on online NP programs. When not working she likes to read, bake, and spend time with her family.

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